Dear community,
I am currently working on a proposal focusing on cancer-associated fibroblasts (CAFs) from malignant pleural mesothelioma (MPM). In my search among commercial cell line providers, I have encountered difficulty in finding a commercial cell line of pleural CAFs. Could anyone provide information regarding a commercial fibroblast cell line isolated from a patient with MPM? Alternatively, a commercial cell line of fibroblasts (CAFs) isolated from a patient with lung cancer would also be suitable. Despite extensive searching, I have yet to locate a commercial cell line of MPM or lung cancer CAFs.
Thank you in advance for any assistance or insights you may offer.
Dear Dr. Carlos Alberto Orozco Castaño
I had come across Human lung adenocarcinoma CAFs which are isolated from human lung tumor tissue. You may procure these cells from the link below.
https://www.neuromics.com/caf117
The datasheet for the cell line is given below.
https://www.neuromics.com/ittrium/reference/D8x10ebfx8x1/Datasheet.pdf
Regards,
Malcolm Nobre
Thank you both for your recommendations. I reached out to AcceGen regarding cell lines and examined the Neuromics lung CAF cell line. While it is indeed suitable for our purposes, it comes at a considerable cost. My concern lies in its limited expansion potential, typically spanning only 3-5 passages.
https://www.creative-biolabs.com/car-t/targeting-cancer-associated-fibroblasts.htm?gclid=EAIaIQobChMI-c_Gs5qKhgMVzaSDBx3HTABUEAAYASAAEgLPX_D_BwE
and
https://www.creative-biolabs.com/car-t/googlecustomesearch.aspx?key=malignant%2520pleural%2520mesothelioma&ty=google&page=2
- Badges
- Science topic
- Similar topics
- Biological Science
- Immunology
- Antibodies