Is the expression of active SARS COV2 of Membrane protein in bacterial system feasible?

21 March 2023 1 4K Report

I am trying to express the soluble fraction Membrane Protein SARS Cov2 in E. Coli. I am getting only monomers while it's the dimer form that is active. Literature that I have come across have used yeast and mammalian expression systems only. I want to know if it can be expressed in E. Coli. If not, why?

Akshaya S V

Sebastian Schmitt

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