Has anyone had any experience with storage tissue in RNA later for RADseq? I know that RNA later is suitable for DNA storage, but was wondering about the quality or any complications that might arise.
It ought to give you decent enough quality for any DNA sequencing method. But if you have a choice, start with the DNA made from fresh tissue sample. Before undertaking a large sequencing project, you would want to begin with high quality starting material by taking all the precautions to yield best quality material.
Thanks for your response! Unfortunately we need to store the sames for a while before we run them, but hopefully they will be fine in the -80C with RNA later!