Yes this is possible

Hello,

You can have a look at:

https://www.emsdiasum.com/wetsem-for-scanning-electron-microscopes

maybe other companies have also such systems.

I had worked with QuantomiX cells (see reply by Nicolas Barois ). No special holders. Easy to use, just follow directions. But they are useful for special range of specimens, such as suspensions (particles, cells), emulsions (phases should differ in mean Z number), food, ets., - specimens that could be pressed against a window and give good representation of their structure.