It is possible to measure AC cells (protein) with OCT in uveitis (so traumatic inflammation could be measured) as demonstrated in vitreo and in vivo by Li et al: www.iovs.org/content/54/1/258.full
To gain a better understanding inflammation (in uveitis or after trauma for that matter) laser flare photometry values (“flare”) as a feature is necessary. However, to identify relationships between flare and other patient and disease (trauma) characteristics; to describe changes in flare during course of disease; and specifically to determine whether elevated flare is predictive of subsequent adverse events after trauma is interesting but I think you would be better off using laser flare photometry.
A study comparing AC OCT and laser flare photometry would be a great asset.
High-Speed Optical Coherence Tomography As A Reliable Adjuvant Tool to Grade Ocular Anterior Chamber Inflammation
Igbre, Ann O. MD, MPH*; Rico, Mario C. MD†; Garg, Sunir J. MD‡
Collapse BoxAbstract
Purpose:
To evaluate the high-speed anterior segment optical coherence tomography (AS-OCT) grading of the AS inflammation in patients with ocular inflammation.
Methods:
A retrospective consecutive case series study. Patients with clinically visible AS inflammation in at least one eye underwent AS-OCT (Visante; Zeiss Meditec) with three to eight line scans per eye, performed by a trained masked examiner. The images were reviewed for hyperreflective spots, noise, and artifact, and these were correlated to clinical examination.
Results:
Seventy-eight eyes of 41 patients were imaged. Forty-seven eyes had anterior chamber cells on clinical examination, and 68 had hyperreflective spots visible on AS-OCT. There was a significant correlation (Spearman r = 0.7274) between clinical examination and Visante OCT images. Several patterns of inflammation and artifacts were apparent.
Conclusion:
The AS-OCT is a promising technique for grading anterior chamber cells. There was a significant correlation between clinical examination and Visante grading.