Is it possible to check the Acute toxicity of CCL4 in Olive oil (1:1) directly after 24 hrs of CCl4 administration (1ml/kg, i.p; CCL4 in Olive oil; 1:1) in Toxic Group of Mice instead of giving Olive oil (1 ml/kg, i. p.) for 6 days and on 7th days CCl4 (1ml/kg, i.p; CCL4 in Olive oil; 1:1)?
Nikola M Stojanovic
YES it is! I dont understand how didnt you found numerous articles on that subject?!
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Pavle Randjelovic
I agree with Nikola. You don't have to give olive oil 6 days. it is just for control. Acute toxicity is after 24 h after CCL4 administatrion regardless of prior treatment.
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