Ashu Gupta

5 Questions 7 Answers 0 Followers

Questions related from Ashu Gupta

How can I dissolve active pharmaceutical ingredients of paracetamol (Acetaminophen) to induce hepatotoxicity in mice/rats (PCM: 500mg/kg b.w., p.o.)?

I am trying to dissolve API of Acetaminophen in Saline/Water to induced Hepatotoxicity in Mice/Rats. But it not dissolved. PCM is soluble in Ethanol and DMSO. May I use Ethanol/DMSO to dissolve...

08 August 2014 6,809 22 View

Is it possible to check the acute toxicity of CCL4 in Olive oil (1:1) directly after 24 hrs of CCl4 administration?

Is it possible to check the Acute toxicity of CCL4 in Olive oil (1:1) directly after 24 hrs of CCl4 administration (1ml/kg, i.p; CCL4 in Olive oil; 1:1) in Toxic Group of Mice instead of giving...

08 July 2014 4,664 3 View

In-vitro DPPH antioxidant assay - can anyone help?

I am exploring antioxidant activity of a liquid sample using 0.1mM DPPH (3.94 mg in 100 ml) in ethanol. prepared different concentration (5, 10, 25, 50, 100 microgram per ml) of test and ascorbic...

31 October 2013 5,608 3 View

How do you make different concentrations (10, 20, 30, 40, and 50 microgram per ml) of a New Drug for In-vitro Antioxidant activity?

I want to make different concentrations (10, 20, 30, 40, and 50 microgram per ml) of a New Drug for In-vitro Antioxidant activity. The new drug is in liquid form. I do not know its concentration.

19 September 2013 9,785 22 View

Which is the right for 0.1mM DPPH Solution preparation?

Which is right for 0.1mM DPPH Slution preparation: 1: 22.2 mg in 1000 ml. or 2: 1.9 mg in 100 ml

16 September 2013 3,796 54 View