I have prepared chitosan nanofibers. Wanted to crosslink it with glutaraldehyde. After cross-linking, shall I keep it in open environment to remove acetone from the nanofibers ? I don't have any oven facility. Does chitosan will react with atmosphere and break or dissolve ??
Planning to crosslink chitosan by dissolving glutaraldehyde in acetone.
I'm new to this. Please help me in figuring out the solution
Thanks
Chitosan is a very stable polymer, and your approach should not have any issues. However additional washing with water or acetone after cross-linking is needed to remove unreacted glutaraldehyde .
Whenever glutaraldehyde is used as a crosslinking agent with normal chitosan the nature and stability of the crosslinked chitosan varies with the amount of crosslinking agent. Quantity of glutaraldehyde has a very strong effect on the strength and the mechanical properties of chitosan. I feel storing crosslinked chitosan for a long time outside will have fatigue effect on the fibers. also the fibers may become brittle.
All these depends on the amount of chitosan and glutaraldehyde.
ALL THE VERY BEST!!
All depends on the molecular weight and degree of deacetylation. Unless you are doing degredation they need to complelety dry in a supercritical point drier or freeze dried to weigh them prior to conducting degradation and afterwards as well.
- Badges
- Science topic