How to convert C++ to matlab m file?

03 April 2017 4,804 3 View

Feature selection SVM-Recursive Feature elimination (SVM-RFE) with Libsvm, the accuracy result is worse than without feature selection, why?

I'm trying to use SVM-RFE with libsvm library to run on the gene expression dataset. My algorithm is written in Matlab. The particular dataset able to produce 80++% of classification accuracy...

05 June 2015 454 7 View

Can anyone share the knowledge regarding the new pathological change?

Please share your precious knowledge regarding the new pathological change of cancer based on gene expression data. Where I can download the related dataset for this research, and how to...

10 November 2014 7,834 3 View

Where can I download the SVM-RFE code in matlab?

07 August 2014 2,129 8 View

How does the Harmony search work for feature selection?

I am a bit confused with the Harmony search for feature selection. Hopefully the expertise here can kindly help to answer my queries. Where should I fit the data set into theHarmony search? Can I...

05 June 2014 5,154 3 View

Can anyone shed some light on Matheuristics?

Is my understanding, Matheuristics is the interoperation of Meta-heuristics and Mathematical programming. What is the advantage and disadvantage of Matheuristics?

05 June 2014 9,559 1 View

Can someone explain what meta-heuristic and heuristic approaches are?

What is the difference and example?

05 June 2014 1,697 4 View

May I know what is the difference of global and local search in term of machine learning and computer science?

Global search vs local search.

04 May 2014 3,994 11 View

What is the difference between supervised, unsupervised, and semi-supervised feature selection algorithms?

Understand that the development of supervised, unsupervised, and semi-supervised feature selection are depend on the class labeled in a data set, either labeled, unlabeled or partially labeled....

02 March 2014 5,714 7 View

Are there any suggestions for software applications to conduct a feature selection algorithm?

There is a lot of software to run the feature selection algorithm, e.g. WEKA, Matlab, and etc. Can anyone please advise which is the best to run the a gene selection analysis? And what is the...

02 March 2014 2,419 5 View

Is it possible for two human neuronal cell lines to have different gene sequence for the same protein?

I am looking at the ATP1A2 (Sodium/Potassium ATPase alpha subunit 2) in two human neuronal cell lines. Expression levels of this protein seems to be almost equal when detected by one antibody....

01 March 2021 3,607 3 View

Genome-wide gene identification protocol ?

Is there any book chapter/book, webpage or research article available to understand genome-wide gene identification?

28 February 2021 8,095 1 View

Any specific pipeline or parameter to analyse total transcriptomics study of brain tissue samples?

I have two groups of brain samples, control and treated for example. It was total RNA nova seq sequencing. I tried all the available pipeline like: star+rsem+deseq2, Hista+stringtie+cuffdiff,...

27 February 2021 356 6 View

RNA-seq DEGs downstream analysis and reporting in literature?

I used EdgeR to get the list of DEGs (differentially expressed genes) from my liver RNA-seq experiment. I have done the gene overrepresentation and GSEA based pathway analysis. I am currently...

23 February 2021 8,969 1 View

Could you please suggests a tutorial or paper or any other materials to learn multiple gene expression in TCGA and GTEx databases?

I would like to analyze multiple gene expressions in normal and cancer tissue by using the data in the TCGA and GTEx databases. Please suggest a tutorial or paper showing step by step analysis of...

23 February 2021 9,007 3 View

Are there any databases for gene co-expression or expression pattern clustering?

I am currently working on gene clustering based on co-expression pattern in mouse brain. The problem is I do not have some solid way to test my result. Are there any suggestions for databases...

22 February 2021 4,374 3 View

Which CpGs have a significant effect on gene expression?

It is known that methylated CpG around TSS decreases gene expression. However, It is difficult to know exactly which CpG has a greater impact on gene expression. Are there any databases known...

20 February 2021 5,634 3 View

I can detect my protein but the encoding DNA sequence has stop codons within. Should I ignore the stop codons?

I constructed a synthetic DNA library (scFv, VH-VL orientation) with a 3' reporter and 8x histag. I cloned and expressed this gene following which I performed an ELISA. The ELISA results suggested...

19 February 2021 7,006 5 View

Purification of proteins from baculovirus-infected insect cells?

18 February 2021 6,665 6 View

Found that there was a multiple band when amplifiying targeted gene ?

i few days ago amplified specific gene using PCR with specific primers, but there was a multiple band in electrophoregram i found. out of 10 sample amplified, there was multiple band and there was...

18 February 2021 5,131 5 View