Organic acids peak at similar RT using HPLC?

My colleague doing the organic acid detection using pelkin almer HPLC unit, RP-HPLC, UV detector. But she got difficulties because some of the organic acid peak were existed at similar RT...

29 December 2020 2,843 5 View

Does society influence on language or language influence on society? How?

The public question is to all experts of linguists, applied linguists and sociolinguists. This helps to figure out the impact of society in language and the impact of language in society.

28 June 2020 3,048 3 View

How to calculate the sample size in muscle assessment studies?

We usually take the sample size from previous literature while working on muscle function assessment using some non-invasive technique like electromyography or mechanomyography. Any one knows...

06 February 2019 6,425 2 View

In disinfection process, how can a certain disinfectant target only pathogenic microorganism?

I understand that disinfection is to eliminate most harmful microorganisms from objects; while sterilization is to to kill ALL microbes - whether harmful or not. I wonder how can a certain...

14 January 2019 1,836 3 View

Ground water model in agricultural watershed to study the fluctuation in groundwater table because of water withdrawals from wells?

16 May 2017 6,944 9 View

Can we obtain antibody against certain toxin in bacteria and how ?

07 August 2016 7,982 6 View

Lib-SVM Classifier technical question:

22 April 2016 907 2 View

Hi, Does any one can confirm or suggest these two photos are for Bosmina coregoni obtusirostris female and male?

The first one which is female carrying eggs and the second one which I think is a male but not sure!

18 February 2016 270 2 View

How can emotions be calculated by voice? What factors are involved in this?

Emotions have different states (sad, happy, angry, neutral), how can these emotions be calculated by voice for an intelligent machine?

06 December 2012 184 1 View

What is the difference between Classification Map and Taxonomy Map

I would like to do a systematic review for the literature review but i found 2 maps. 1- Classification Map. 2- Taxonomy Map. What are the differences between them in term of number of papers that...

01 January 1970 9,282 12 View

What solvent can I used for Paal Knorr reaction between 6-amino hexanoic acid and 2.5 hexanedione?

I am try to make the Paal Knorr reaction between 2.5 hexnedione and 6-amino hexanoic acid, my problem is type of solvent to use, because 6-hexaminohexanoic acid is soluble in water but I am not...

02 March 2021 4,443 2 View

Does Napabucasin soluble in dichloromethane and in ethanol?

I need to prepare a solution of Napabucasin (inhibitor of cancer cell stemness) in dichloromethane. The drug is expensive, so maybe somebody already tried to do it. If it is soluble, what is the...

02 March 2021 9,945 3 View

What is the state of the drug inside solid lipid nanoparticles (SLNs)?

I am a little confuse with the mechanism of solid lipid nanoparticles (SLNs). The main point of encapsulating drugs into SLNs is because some drugs have low solubility in water. Therefore, SLNs...

01 March 2021 3,703 3 View

Is CD44 degraded in lysosome together with hyaluronan after CD44 mediated endocytosis of hyaluronic acid?

Also when RHAMM binds hyaluronic acid, they get internalized, will RHAMM also be degraded? Or both CD44 and RHAMM will be transferred back to the cell membrane? Asking for breast cancer cell line...

01 March 2021 8,169 2 View

I want to performe MALDI-TOF MS for bacterial identification, I would appreciate it if anyone can tell me the matrix solution preparation protocol ?

based on what I've studied on multiple papers, for peptide and protein identification Alpha-cyano-4-hydroxycinnamic acid (CHCA) is an appropriate matrix to use, I also know that the CHCA powder...

26 February 2021 6,799 3 View

Do you kow of any database containing data on retention time, log P and polarizability for a large number of molecules?

Hi, I am a chemistry undergraduate doing my dissertation project on HPLC. In my project, I need to predict the HPLC retention time of 20 aromatic molecules, the calibration set. To do this I will...

24 February 2021 2,602 1 View

Can I use acetic acid with an ELITE WAX Perkin Elmer column for Gas Chromatography?

Hi! I would want to know if I can use acetic acid with an ELITE WAX Perkin Elmer column for Gas Chromatography. This column has a polyethylene glycol phase, but I can't find the manual to check...

22 February 2021 730 2 View

Can you perform the Murexide test on samples fixed in Formalin?

I have a fixed sample and would like to use the murexide reaction to test for uric acid composition. I no longer have fresh samples

22 February 2021 1,328 1 View

Is there an ideal incubation time of RGO-modified SPCE before subsequent use, i.e., electrochemical characterization or further modification?

I notice that upon washing and air-drying of my RGO/SPCE surface and characterizing again via DPV, the current response towards ferricyanide probe significantly decreases. My worry is that the...

22 February 2021 5,324 3 View

How to seperate PEG-4000 from aqueuse phase ?

Hello everyone , Please tell me if It possible to seperat POlyethelyn glycol -4000 from an aqueuse media by other ways rather heating . I have tried salting out by electrolyte solution to...

22 February 2021 7,285 5 View