How can SARS CoV 2 viability/infectivity assessment find in vitro models that perform better (eg. in term of sensitivity) than cytopathic Vero E6 assays? Are there cell models expressing ACE2 receptors for such task? Which the limits upto now? Aerosol sampling devices preserving viral viability/infectivity are available now.
Article Viable SARS-CoV-2 in the air of a hospital room with COVID-19 patients
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Please go through the airborn infection ( space velocity ) through aerosol spreading - https://www.researchgate.net/profile/Jaydip-Datta/post/Do_We_belive_that_spreading_death_of_people_by_Covid_19_is_due_to_severe_damage_of_Environmental_Sustainibility/attachment/5ee2318f32fcf50001920eb2/AS%3A901233116200960%401591882127816/download/200409PIAaer_z03.5e8cf8b6070ef.png
PLEASE REFER TO ONE OF OUR PUBLICATION OF LAB:
Clinically relevant cell culture models and their significance in isolation, pathogenesis, vaccine development, repurposing and screening of new drugs for SARS-CoV-2: a systematic review.
Kumar S, Sarma P, Kaur H, Prajapat M, Bhattacharyya A, Avti P, Sehkhar N, Kaur H, Bansal S, Mahendiratta S, Mahalmani VM, Singh H, Prakash A, Kuhad A, Medhi B.Tissue Cell. 2021 Jan 26;70:101497. doi: 10.1016/j.tice.2021.101497. Online ahead of print.PMID: 33550034