Hi Everyone,
I am trying to implement a PBPK model based on the paper
Physiological Modeling and Extrapolation of Pharmacokinetic Interactions from Binary to More Complex Chemical Mixtures.
Uptil now I have implemented it in R, using the DeSolve for solving the differential equations. The problem is getting the output right. I am using the equations and models provided in the paper with no luck. If some has implemented the same in any language and is willing to share the code for reference purposes I would be grateful, I am also attaching my R code with this question just in case someone can find what I am doing wrong.