I would recommend searching in Pubmed. Put in the relevant search terms adjust the year filter to more recent years and see the current literature published on the topic. You may also check Cochrane Library

Dear Alka

Please look at the Cochrane Handbook for Systematic Reviews of Interventions. It is very useful.

In brief, and based on the PRISMA guideline, first, you need to clear your question and turn your free question into a structured question, for which you can use the PICO (Population, Intervention, Comparison, Outcome) format. Then, you have to determine the eligibility criteria based on your PICO and then extract the relevant keywords, formulate a search strategy, and start your search in the databases you are considering, and choose the databases based on your topic. The routine databases can be PubMed, Scopus, Web of Science, Cochrane, and Embase for your topic.

After completing the search, you should enter the results into a data management software such as EndNote and start the screening process. In the following, after the final articles are determined, you should perform a quality assessment, data extraction, and analysis. I recommend that you use the PRISMA checklist to report your results.

Feel free to ask any questions.

Cheers

1. Is there a need for a new systematic review?

First, you need to determine if there is a need for a new systematic review on this topic. You can do this by searching for existing systematic reviews on PubMed and Google Scholar. If you find a recent systematic review on the same topic, you should carefully consider whether your review would add any new value. For example, your review could focus on a specific subgroup of patients (e.g., children, adults, or patients with a specific type of TOF repair) or on a specific outcome (e.g., mortality, quality of life, or long-term cardiovascular health).

2. Develop a focused research question.

Once you have determined that there is a need for a new systematic review, you need to develop a focused research question. This question should be specific, measurable, achievable, relevant, and time-bound. For example, your research question could be:

What are the most effective and safest treatments for pulmonary regurgitation in adult patients with repaired TOF?

3. Develop a search strategy.

Next, you need to develop a search strategy to identify relevant studies. Your search strategy should include a combination of keywords and medical subject headings (MeSH terms). You should also search multiple databases, such as PubMed, Embase, and Cochrane Central Register of Controlled Trials.

4. Select relevant studies.

Once you have identified a set of potential studies, you need to screen them to determine whether they meet your eligibility criteria. Your eligibility criteria should be based on your research question and should be clearly defined in your protocol. You may exclude studies that are not published in English, that are not full-text articles, or that do not focus on adults with repaired TOF.

5. Extract data from the included studies.

For each included study, you need to extract relevant data, such as the study design, patient population, intervention, outcome measures, and results. You can use a data extraction form to help you organize the data.

6. Analyze the data.

Once you have extracted the data from the included studies, you need to analyze it to answer your research question. This may involve using statistical methods to synthesize the data from the different studies.

7. Write a systematic review report.

Your systematic review report should summarize the findings of your review and discuss the implications of your findings for clinical practice. You should also discuss the limitations of your review and identify areas for future research.

Highlighting the uniqueness of your systematic review

If there is already a systematic review on the same topic, you need to highlight how your review is unique. For example, your review could focus on a specific subgroup of patients, a specific outcome, or a specific type of intervention. You could also use more advanced statistical methods to synthesize the data or to assess the quality of the included studies.

Overall, conducting a systematic review is a rigorous and time-consuming process, but it is a valuable way to synthesize the evidence on a particular topic and to inform clinical practice.

I am ready for any help you are need.

U can send me in private if u want.

Thank U Dr. Alka.