I was wondering where I could get hold of anti-insulin Abs with no cross reactivity to proinsulin?

22 December 2014 1 9K Report

Any ideas?

Article Development of a novel ELISA for human insulin using monoclo...

You should be able to find something suitable but it depends on the nature of your experiments. For example, if you are interested in performing insulin measurements by ELISA, commercial suppliers such as Alpco sell kits that will detect human insulin but will not interact with intact proinsulin.

i have encountered various versions of monoclonal antibodies that recognize partially processed proinsulin to varying degrees. Based on your needs, look carefully for binding profiles.

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