Everything may happen in Biology but at present is more "likely" that amyloid deposition affects the phsyiology of ion tansport and this, no doubt, would affect neuron funtion and fate.

Thanks Rafael

I was not even thinking about how amyloid deposition would affect ion transport ..

Some studies exists to have a better understanding about amyloid agregation and pH regulation. It seems to be that Cu(II) and Zn (II) abundance is a main feature for fast agregation, but it's an in vitro info. If you want some ideas, read that and bibliography connected. Article Effect of ionic strength on the aggregation kinetics of the ...

Thanks Jonathan