Human genetic polymorphisms - the best database?

More Václav Brázda's questions See All

Is there a simple alternative to separating genomic DNA from short DNA fragments?

other than DNA gel extraction

09 February 2023 8,339 0 View

The best method for DNA isolation from fish samples?

What is the best method for DNA isolation from fish samples? Any experience and/or tips how to improve yield of genomic DNA from fish samples? What tissue is the best source? How much DNA is...

31 January 2023 5,759 1 View

More G-qvadruplexes in genomes that expected?

The number of stable G-quadruplex prone motifs was strongly underestimated in the previous version of the human X-chromosome: Novel G-quadruplex prone sequences emerge in the complete as... Will...

07 October 2021 6,981 0 View

Entomophtora on Macrolophus bug?

Hello, we are growing tomato in the greenhouse. Macrolophus pygmaeus is our main tool to control pests. We are at the moment for some un-known reason struggling to build up a strong popoulation of...

16 March 2020 7,986 6 View

Macrolophus pygmaeus - how to solve the breeding problem?

Hello, we are facing to some problem with Macrolophus pygmaeus population in the greenhouse. We have introduce Macrolophus bug into the tomato greenhouse 5 months ago and reintroduce it about 4...

16 March 2020 7,216 3 View

Are there any recent publications stating that the diameter of a microtubule with 13 protofilaments is ~25 nm?

I could find very old electron microscopy articles (like Gall 1966: Microtubule fine structure), but wanted to cite also some papers from last decade. But no one is citing the common fact that...

21 March 2019 3,120 3 View

Where is the water in granites?

I am interested in clay minerals formed in plutonic rocks (mainly granites) prior to obvious weatherig processes. If we look at wet analyses, there is mostly 1 wt. % "H2O+" (even in samples from...

01 December 2017 3,677 6 View

Who is responsible for this damage on an apple furit? Is it Cydia pomonella?

Hello, I need your opinon about pest which is causing damage on apple fruit. It is usually a hole with the cavity underneath. There are no excrements nor on fruit surface close the hole neither in...

15 September 2017 9,779 2 View

Does somebody know what kind of tomato virus is this?

Hello everbody, I would like to find out what virus species attacked tomato. Please see pictures. Thank you for help.

09 February 2017 1,109 3 View

Can someone give me advice about the application of Spintor Fly?

We will test this product within some trails in central Europe. I can´t find any materials in English. How to spray with this product?

17 May 2015 9,800 4 View

Who of all the Global Scientific community will help me Prof. Dr. Yoshida make way for TPEOM, MEC ~EMC to return the atmospheric gases to the norma ?

TEP presentation caption (The Environmental Project) Re: Why should Washington’s DC, or any country government point of location think of as nowadays of as to being 'tomorrow as to come! if it...

03 August 2024 2,484 1 View

Which is more important: The human factor or the technological factor in combating climate change?

On a personal note, even though technology has attracted a lot of interest and funding to combat climate change, it is becoming more and more clear that taking care of the "Human Dimension" is...

02 August 2024 6,773 12 View

How to retain the a GFP tagged gene expression in stable cell line?

Hello , I established a stable cell line expressing GFP tagged to a centrosomal gene having G418 drug selection marker. I validated the stable line by IFA and Western blotting, results are fine....

29 July 2024 5,007 0 View

In terms of chaos, what is the necessary and sufficient condition for authoritarianism, permanent or temporary, to come to exist and persist?

Since 2016 Brexit, the world needed to change the thinking behind traditional democracy as the democratic landscape changed, yet traditional democratic thinkers and actors have been acting as if...

28 July 2024 6,515 1 View

What is effective targeted chaos?

Perfect democracy thinking assumes no chaos so no need for independent rule of law system and liberal democracies assume the possibility of normal democratic chaos that can be sorted out by an...

28 July 2024 473 1 View

I want to get updates regarding international law, international trade law, international institutions and human rights etc?

Please send me updates regarding the above-mentioned areas in the question mark?

28 July 2024 5,197 3 View

Are there any alternatives to PhenoScanner?

I am currently conducting a mendelian randomization study, and I was attempting to use PhenoScanner to look for potential confounders associated with the selected SNPs (any SNPs significantly...

23 July 2024 5,703 0 View

How does the human microbiome influence health and disease, including implications for personalized medicine and microbiome-targeted therapies?

Probiotics related.

22 July 2024 1,707 2 View

How can microbial engineering techniques be used to enhance the functionality and efficacy of probiotics ?

through genetic modification or metabolic engineering? Is it helpful, good for health ?

22 July 2024 7,811 4 View

What is human-computer interaction (HCI)?

22 July 2024 10,056 2 View

Syed Sameer A

The one and only :: https://www.ncbi.nlm.nih.gov/snp/

And :: http://projects.tcag.ca/variation/

Pascal Rihet

besides, you can get information from ENSEMBL:

https://www.ensembl.org/index.html

and you can get annotation of the SNPs using variant effect predictor (VEP):

https://www.ensembl.org/info/docs/tools/vep/index.html

Václav Brázda

Thank you. I will try.

Matej Lexa

No specific recommendation, however, I have recently come across this resource: https://gnomad.broadinstitute.org/