The compound 1,4-dihydro pyridine oxidized in the presence of potassium permanganate and microwave. After oxidation, the organic product and manganese dioxide are formed, and the two substances are solid. I need a way to separate the two substances.
Separation by Extraction: Add Dichloromethane to the residue, stir and filter. Add anhydrouis Na2SO4 to the Dichloromethane solution, stir and filter. Finally remove Dichloromethane by evaporation and the corresponding pyridine will be obtained.
Separation by Extraction: Add Dichloromethane to the residue, stir and filter. Add anhydrouis Na2SO4 to the Dichloromethane solution, stir and filter. Finally remove Dichloromethane by evaporation and the corresponding pyridine will be obtained.
Find a solvent in which your product is soluble and vacuum filter the suspension through celite preferably on filter paper. MnO2 from a permanganate oxidation is a very fine solid and can be difficult to remove, but this should work.
Find a suitable solvent ( ethyl acetate, methylene chloride, alcohols ,...etc).
to dissolve ONLY the product , filter and remove Mno2 or using centrifuge.
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