Muritala Olusola hello!

You ding well

First of all check your dlg file if possible so make it again and one thing specified your path where you save all the files for docking.

Thank you Waseem Ahmad for your suggestions,I have checked and also specified my work path which I named ADTWORKSPACE. I was thinking may be I did not get the editing of the parameter files properly or what do you think can be the problem. Thank you once again

May be you excluded some steps or parameters

Try running autogrid to get the MAP files before running autodock. I hope this helps.

I did that also

The problem is that not all the needed maps have been created, in the "grid" window, there is the "set map types" option, select it, and write the missing map atom.

best wishes.

Diego Contreras thank you, absolutely you should choose your ligand in "set map types", I missed this step and got the missing map error message

my pleasure, best regards

Thank you Diego Contreras

So what's the best solution？

Hello Muritala Olusola

In the event of the appearance of this issue at the existence of all required maps in your directory, you can also manually check the content of your .dpf file and verify the names of all maps.

I had a similar error with the desolvation map. I used the long name for my .d.map file, and when I opened the .dpf file I found that it contained the following description of the desolvation map: "desolvmap 1qkm_wo_non-std_rsdus.d.map# desolvation map". So, the name of my .d.map file took the whole space up to the "#" sign, and probably AutoDock4 wasn't able to recognize the correct name of the file. The addition of a single space between the name of the map file and the "#" sign as follows "desolvmap 1qkm_wo_non-std_rsdus.d.map # desolvation map" resolved my problem.