How to remove tosyl acid from reaction mixture?
Tosyl acid itself water soluble.So we can give water wash to remove tosyl acid.
load simply your sample to your column. since it is very polar it will stick on the silica.
dilute with pentane and filter
See synthesis of drugs in www.drugsyn.org
Dissolve your compound in some solvent and then filter. Do this process if your desired product is also watersoluble.
Wash with 50 percent NaOH solution, then wash with water
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