I'm trying to find the most simple conditions to quantify nicotine in e-cigarette liquid samples. I have an HPLC-UV (Shimadzu LC2030C plus) with a C18 column (VP-ODS shim pack, size 150l x 4.6, ID 0.3 mm). Thank you.
Hi,
Hope some of these articles and cross-references be of help to you:
Barhdadi S, Desmedt B, Courselle P, Rogiers V, Vanhaecke T, Deconinck E. A simple dilute-and-shoot method for screening and simultaneous quantification of nicotine and alkaloid impurities in electronic cigarette refills (e-liquids) by UHPLC-DAD. J Pharm Biomed Anal. 2019 May 30;169:225-234. doi: 10.1016/j.jpba.2019.03.002
Moghbel N, Ryu B, Steadman KJ. A reversed-phase HPLC-UV method developed and validated for simultaneous quantification of six alkaloids from Nicotiana spp. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Aug 1;997:142-5. doi: 10.1016/j.jchromb.2015.06.006
El Mubarak MA, Danika C, Vlachos NS, Farsalinos K, Poulas K, Sivolapenko G. Development and validation of analytical methodology for the quantification of aldehydes in e-cigarette aerosols using UHPLC-UV. Food Chem Toxicol. 2018 Jun;116(Pt B):147-151. doi: 10.1016/j.fct.2018.04.021
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