How to monitor half life of peptides?

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How researchers design primers for a novel virus's genome sequences?

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Unusual intensity drop in some sections of chromatograms in DDA?

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Recovery rate after peptide desalting using Sep-pack C18 1 cc Vac Cartridge?

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Is it possible to conjugate an NHS ester to the N-terminus of a peptide ON RESIN?

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How to cacualte the creep life of polycrystal with CPFEM?

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I found trouble to run MD of my peptide with PTM in different force field. In Charm-GUI, it cant recognize the engineering residue. What can I do now?

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Guobing Xiang

Anukana

Half live for(in) what kind of process?

Sorry for asking!

Andrei Blasko

For biological activity you need a bio-assay method. For chemical and physical degradation, PRLC, SEC, CEX and CZE chromatographic methods.

Rob Keller

Dear Anukana,

While being busy on something else I ‘stumble’ on the following site called PEPLife:

http://crdd.osdd.net/raghava/peplife/

Select the download option and subsequently reference:

http://crdd.osdd.net/raghava/peplife/ref.php

Here you find references to numerous studies. Possibly you find a desired and for you useful procedure.

Good luck!