there are several methods to making animal model of diabetes, but if we want to make a model of diabetes with desirable blood glucose, how it is possible?
I use 0,1 mL/100 g body weight alloxan to produce diabetic rats, but glucose concentration in blood plasma vary from 7-8 mM/L to 18-20 mM/L. Therefore, the glucose concentration in blood depends not only on alloxan amount, but other factors, which I cannot define now.