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I want to develop a model of type 2 diabetes mellitus by daily administration of sucrose in rats. but there is no verified protocol for it.
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As we know, rats are very resistant to rise in blood glucose and lipids via high-fat diet. so, what is the lowest effective percentage of fat in the diet of them for the induction of type 2...
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there are several methods to making animal model of diabetes, but if we want to make a model of diabetes with desirable blood glucose, how it is possible?
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