I would like to estimate a translog production frontier function. For that I want to normalize my variables relative to the mean ( i suppose that means subtracting the mean from the variable itself? i understand there are other ways to normalize as well like z=X-Xbar/sd or X-Xmin/Xmax-Xmin as well). When i do so, it creates very small and negative values in both dependent and independent variables. Also after normalization when i log transform, there are even more zero and negative values. My question is, can i still run a multiple regression with negative and zero values (particularly in dependent variable), and does the interpretation of the coefficients change? Can someone please assist. Thanks