Hello, we have solvent purifier system in our lab. But There is some unwanted results for our experiment. We are suspecting purity of solvents. Are there any simple methods to detect water in THF?
Dear Berkay Şahin, the simplest technique is based on measuring the refractive index increment but I couldn't find a reference right now. The following documents use NMR and colorimetry. My Regards
https://doi.org/10.1002/bkcs.10689
https://doi.org/10.1039/C2CC31118F
Dear Berkay Şahin, the simplest technique is based on measuring the refractive index increment but I couldn't find a reference right now. The following documents use NMR and colorimetry. My Regards
https://doi.org/10.1002/bkcs.10689
https://doi.org/10.1039/C2CC31118F
Dear Berkay Sahin, there is a simple way using MgSO4 or Na2SO4 and mix it with THF. If the MgSO4 is swollen then there are traces of water in THF.
Hi,
The presence of water or other molecules dissolved in THF can change the refractive index of the solvent. So a simple refractive index measurement allows you to check the purity of your solvent. If the refractive index of THF is different from 1.408 then it should be purified. If the If the vial has already been opened, it contains impurities, mainly hydroperoxides and peroxides which may explode if dried or concentrated.
With my best regards
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