Hello, I am currently working on my project for my thesis in Pharmacovigilance. I found a case when a diabetic patient consumed glimepiride while at the same time he/she had Cirrhosis also CKD. I am confused about how to answer the fifth question, that is, "Are there alternative causes (other than the drug) that could on their own have caused the reaction?". Can I answer these by "Yes" because some resources stated that CKD stage 5 (kidney failure) dan Chirrhosis might cause hypoglycemia but on the other hand some sources stated CKD and Chirrosis as risk factors.
From your perspective should I answer it as a "No" or"Yes" Or "Do not Know"? Thank you, I am looking forward to your reply.
When the amount of sugar in a person’s blood is too low to provide their body with sufficient energy, it can lead to something called hypoglycemia. Hypoglycemia is defined as a blood sugar level under 70 mg/dl (3.9 mmol/l) and can result in irritability, confusion, and even seizures and unconsciousness during extreme lows.
the answer to this question, "Are there alternative causes (other than the drug) that could on their own have caused the reaction?" would be Yes. Cirrhosis patients can develop hypoglycemia.
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