How does one cure a long-term headache (more than 2 months), which seems to be secondary to recurrent depression in man?

The headache is located in the following regions of the head: left and right orbitofrontal cortices, lower left temporal cortex, lower left parietal cortex and lower left occipital cortex. The pain switches sometimes from the frontal areas to the back areas of the brain.

Could it be something unrelated to depression?

What are the causal underlying mechanisms of such pain?

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