Petar Dimkov

6 Questions 10 Answers 0 Followers

Questions related from Petar Dimkov

Flupentixol in depression: Which are the underlying mechanisms of action/efficacy?

Flupentixol is a conventional antipsychotic drug (strong D1 and D2-receptor antagonism plus some other actions such as a weak 5-HT2A antagonism). Today it is used as an antidepressant in doses...

15 December 2019 4,549 2 View

How to cure a headache in recurrent depression?

How does one cure a long-term headache (more than 2 months), which seems to be secondary to recurrent depression in man? The headache is located in the following regions of the head: left and...

15 December 2019 4,826 4 View

Coffee and Psychedelics in the Potentiation of Creativity - Common Underlying Mechanisms?

Recent research in cognitive neuroscience shows that the dopaminergic neurotransmission is correlated to creativity (both to the genesis of creative ideas and their elaboration). However, a direct...

15 December 2019 808 1 View

Induced mania by olanzapine and risperidone: which are the underlying pharmacodynamic mechanisms?

The antipsychotic-induced mania is an interesting phenomenon as antipsychotics are typically used to treat mania. Such induced mania occurs mainly with atypical antipsychotics such as olanzapine...

26 September 2017 4,021 7 View

Schizophrenia, pharmacotherapy and negative/cognitive/pseudonegative symptoms: Would an extreme polipharmacotherapy help?

What do you think about a combination of four pharmacological agents from four different classes to ameliorate the negative/cognitive/pseudonegative symptoms of a schizophrenic psychosis,...

23 October 2016 8,799 9 View

Pharmaceutical Cognitive Neuroenhancement: A cheat or what?

What is cognitive neuroenhancement? In short, is not a medical treatment, but rather the personal utilization of pharmaceutical means for a lift of cognitive capacities above the “norm”. The...

01 January 1970 3,256 1 View