I run sequening on a sample and found a pathogenic variant. Then I draw a 3Dprotein model on Swiss-Model for the wild type protein and the mutatnt protein. I don't know how to comment on things like changing protein structure, properties, ---- etc.

Can you please help me?

The change was alanine to proline.

Also I would be gratful if you suggested other softwares.

Thank you

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