How can I remove AlF3 from the Colloidal solution?

Its a colloidal solution of nano materials and AlF3 forms during the reaction and its still exist in the sample even after water washings.

22 July 2020 4,889 0 View

In EFA, if the items do not get loaded under meaningful factors, what should be done?

Say item number 1, 2, and 3 are being loaded under factor A and it seems theoretically meaningful. But another item i.e. item number 4 is also being loaded under factor A and this time it doesn't...

07 May 2020 5,794 11 View

How to convert numerical data into categorical data(Class) ?

Objective : Classification of wheat & Mustard genotypes using support vector Machine (SVM) ? Since SVM can classify on the basis of categorical data(Class) only like low, medium, high; but we...

19 February 2020 6,458 3 View

Which criteria we should use to classify Barley varieties into Resistant to susceptible in case of spot blotch double digit scored data ?

can we use AUDPC value if not why ? or Can we use AUDPC % days = (AUDPC/Days to maturity)*100 Or final double digit scored data if yes then what may the scale ?

30 July 2019 6,346 2 View

How to calculate diffusion coefficient from GITT data? Kindly, explain step by step, if possible?

GITT data was collected using Biologic machine.

02 May 2017 474 6 View

How to calculate concentration of drug soluble in oil by UV Spectroscopy ?

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23 March 2017 458 5 View

Can we clone 1.3 kb insert with end blunt end and other sticky end-- ligation - vector with one end sticky and other blunt end?

I have an insert and vector with one sticky end and other blunt end, It did work when insert size was small but at the time of large size fragment it didn't. Can anybody provide me solution?

25 July 2016 2,466 5 View

How can we define the most suitable herbal seed extraction (Methanolic, water, etc) ?

01 June 2015 2,603 5 View

Does fused chromosome show increased telomere length?

If chromosomes get fused at telomere after shelthrin dysfunction, will this condition show increased telomere length in qPCR method?

07 April 2015 3,385 4 View

Is HPLC an ideal option to know the components of aqueous plant extract?

07 January 2015 7,359 12 View

Does Napabucasin soluble in dichloromethane and in ethanol?

I need to prepare a solution of Napabucasin (inhibitor of cancer cell stemness) in dichloromethane. The drug is expensive, so maybe somebody already tried to do it. If it is soluble, what is the...

02 March 2021 9,945 3 View

What is the state of the drug inside solid lipid nanoparticles (SLNs)?

I am a little confuse with the mechanism of solid lipid nanoparticles (SLNs). The main point of encapsulating drugs into SLNs is because some drugs have low solubility in water. Therefore, SLNs...

01 March 2021 3,703 3 View

How to calculate Ligand-active site distance in a ligand-protein complex from MD simulation?

I have run a MD simulation of a ligand-protein complex in GROMACS using CHARMM forcefield. Reviewer has asked me to calculate Ligand-activesite distance and binding free energy of ligand with...

27 February 2021 4,703 1 View

Do you kow of any database containing data on retention time, log P and polarizability for a large number of molecules?

Hi, I am a chemistry undergraduate doing my dissertation project on HPLC. In my project, I need to predict the HPLC retention time of 20 aromatic molecules, the calibration set. To do this I will...

24 February 2021 2,602 1 View

How to seperate PEG-4000 from aqueuse phase ?

Hello everyone , Please tell me if It possible to seperat POlyethelyn glycol -4000 from an aqueuse media by other ways rather heating . I have tried salting out by electrolyte solution to...

22 February 2021 7,285 5 View

How to analyse monosaccharide compositions from soluble fiber?

I have tried to hydrolyze the sample using 2 M TFA at 100C for 24, 48 h and 120C for 2 h. From these conditions, the HPLC results showed that peaks were not separated into monosaccharide. I found...

17 February 2021 5,230 1 View

No title

Hello. I ask for help - I need to get lithium tetraborate (soluble salt) from lithium carbonate and boric acid. In literature, everything seems to be simple - mix, ignite and - it's done. But it...

16 February 2021 9,523 2 View

Is There are any idea to achieve H NMR signals for swollen compound ??

the samples are not completely soluble - just swelled the solvents that's mean the sample may be partially soluble any suggestion, please

16 February 2021 8,801 3 View

How long does it take to design and validate transition state analogue inhibitors?

Hi, I'm asking from the point of view of designing a research plan: How long (approximately) can it take to determine the transition state structure of an enzyme substrate using kinetic isotope...

14 February 2021 2,610 1 View

Gromacs force field and water model recommended for protein hydrophobic study?

Dear All, I received a comment from reviewer about asking me selection of force field and water model. I choose OPLS-AAL and 3-point water model. They mentioned the combination of OPLS-AAL and SPC...

13 February 2021 1,364 3 View