I have calculated the Initial and final hemoglobin iron (HbFe). Assuming that 6.5% of the body weight (BW-Kg) is blood and the iron content of hemoglobin (Hb) is 3.4%. The formula to calculate HbFe is given below
HbFe= Body weight*0.065*GmsHb/L*3.4%
I have to calculate the iron bioavailability in different groups of rat which were provided with different diet formulation.
I have also measured the level of Hb in each rat
Kindly help me to do this.
Dear Sir. Concerning your issue about the calculation of the bioavailability of iron. Previous laboratory studies have shown that dietary iron during digestion forms two pools: heme and nonheme. Even though human beings absorb heme iron at a higher rate than nonheme iron, the major portion of food iron is nonheme (all grain and vegetable iron plus approximately 60 percent of the iron in meat, fish, and poultry). The absorption rate of nonheme iron can be increased markedly by concomitant consumption of ascorbic acid and/or meat/fish/poultry. These concepts have been incorporated into a model for estimating the quantity of bioavailable iron, the first trace mineral to be thus considered. I think the following below links may help you in your analysis:
https://www.ncbi.nlm.nih.gov/pubmed/7061776
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533300/pdf/ajcn147389.pdf
http://www.coaching-for-health.net/eisenzentrum/studien/bioavailability.pdf
Thanks
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