Hi,
in many spirometer reports there are predictive curves at flow-volume plots (see figures attached to this question). I would like to draw similar predictive curves to the results that I analyzed based on predictive FEV1, FVC and PEF calculated using clinical data (age, weight, height, race, etc.).
My question is about the placement of the maximum flow point (PEF) in x-axis, so at the volume scale.
There are any recommendations for this point?
Should I choose a constant value? I read that the 'time to PEF' should be less than 150 ms, so maybe it would be a starting point to calculate volume where I should put predictive PEF value at the flow-volume plot.
Thanks for any suggestions!
Mateusz
I would suggest you assemble a large population of flow volume plots , then do multiple linear or spline regressions on age ht sex etc for certain curve parameters, eg peak flow, time to return to zero flow, point of inflexion. Then construct a "predicted curve" for a person of certain age/ht/ sex etc do a spline fit using these calculated parameters.
the examples of predicted curves you give are only idealised.
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