How to build a new HMMs from a database (say NCBI)?

05 February 2020 1 6K Report

I am new to HMMs and was thinking to build new HMMs based on the NCBI database(which is available to download) or SILVA, so that it can be used by some other program. Can you suggest any tool which can easily serve my purpose?

Abhijeet Singh

Use HMMER and its command hmmbuild to make profile hmm

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Science method

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