How to analyze the impact of SNPs in NODEL gene from 1000 genome project? We are interested in EUR population? Is it ok? Please write 2 sentences for the methodology of analysis? which software or statistical method to address my query is best and why? Explain and Justify?
Tommaso Mazza
What do you mean for "impact in 1000 genome project"?. Are you interested in the allele frequency in the EUR population? Are you interested in the clinical impact (clinvar)?
For both questions, since the number of interested SNPs are 4, you can easily search them by the dbsnp website. If you are not aware of the dbsnp ids for your 4 SNPs, you can get them through one of the existing genome browser.
https://www.ncbi.nlm.nih.gov/SNP/
https://genome.ucsc.edu/
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