Anticoccidials in feed are used to prevent coccidiosis. However, in Layer and Breeders these cannot use due to negative effects. But what is the actual mechanism involved in reduction of egg production, fertility and hatchability etc.???
Not all anticoccidials do influence layers and breeders. Well known is the adverse effect of nicarbazin. The attached file might help you further.
Article Feed Additives: Do They Add to Animal Welfare? An Evaluation
According to my information, Only Amprolium can used in Layers and breeders. Mostly it is reccomended that use anticoccidials in feed only up to 12 weeks of age.
Very good reference by N.G.Fowler, 1995, probably out of print. Sorry, he did not provide original references but provided the following summary.
Amprolium safest: 700 ppm affects viability at hatch, 1400 reduces hatchability, 2000 affects egg production, 4000 egg quality.
Lasalocid: 75 ppm reduced breeder hactability and fertility
Monensin: Residues in eggs laid by monensin-fed birds 100 ppm/10 days at 40% production reduced fertility
Maxiban (narasin:nicarb): layers 100 ppm/21d reduced feed intake, egg production and hatchability
Salinomycin 25 ppm reduced egg production
60 ppm reduced egg weight slightly, significantly reduced hatchability
robenidine 33 ppm for 10 days (breeders at 40% production) no adverse effects. 33 ppm for 14 days (layers at 41 weeks of age) no adverse effects on birds or production but eggs tainted (2/3 ppm)
I agree with@ Chris Knight
This link of artical is may be useful
Article Production and Egg-Quality Responses of White Leghorn Layers...
Amprolium, the most commonly used coccidiostat, works by depriving the Emeria of thiamine. However, I am not sure if it simply blocks the Emeria from utilizing thiamine or actually reduces thiamine in the patient. When used for breeding birds, it is best to supplement with thiamine, or provide thiamine-rich greens after treatment.
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