The DMF solvent can be tried, and also the excess of the K2CO3 will not affect the protan abstraction reaction. In general, a eq. ratio of 1:1.1 of substrate to base can be used.

You can club K2CO3 or KOH with a phase transfer catalyst using biphasic system!

I agree with Sushil Kumar. DMF/K2CO3 is a good strategy. KOH or NaOH in DMSO have also worked in my lab.

Thanks to all

the excess of the K2CO3  affect the proton abstraction reaction.  eq. ratio of 1:1.2 in DMF of substrate to base can be used.  slight elevated temperature could favour depend on substrate analogue..

One can use  powdered NaOH or KOH (one equiv.) ,  catalytic n-Bu4N+HSO4– (Phase transfer catalyst),  anhyd. THF,  stirring at room temperature, 1 h,   for generation of the anion on "N". This is very good nucleophile for reaction with RX  (alkylation) or ArSO2Cl (aryl sulphonylation). Theoretically half equivalent  of K2CO3 in DMF will do the purpose also. But NaOH gives very good result as observed by us. 

I want to react 2-nitro Imidazole with Benzyl bromide using one equivalent of each with K2CO3(1.1 Eq). Under what condition reaction is possible. 

Dear Nadeem Ahmed Lodhi

Usually the condition used in such cases is 3 equivalent of K2CO3 in DMF with heating at 80 for 4-6hrs. and pour onto water, filter, wash with water

Good luck

I have experience with similar experiment @Nadeem Ahmed, PTC worked good for me. But many of the responses are equally good suggestions.