https://en.wikipedia.org/wiki/Ancylostoma_caninum#Life_cycle

Human get infection of Ancylostoma caninum by skin penetration of larvae and causes cutaneous larval migrans or  creeping eruption or ground itch. They remains under skin and do not develop further more. Rarely, A.caninum larvae may migrate to the human intestine, causing eosinophilic enteritis.    

A (rhetorical) question that arises is: How frequently are non-definitively-diagnosed human infections (cf. eosinophilic enteritis) caused by oral ingestion of embryonated Ancylostoma spp. eggs deposited in the environment by dogs and cats?

Thanks for all

نتقدم بالشكر الجزيل على هذه المعلومات العلمية القـيمة

I fully agree with the answer of Saroj Kumar. We often observe patients with this invasion after returning from the territories of southeastern Asia

One can become infected with Ancylostoma caninum by coming into contact with soil that contains infective filariform larvae. The larvae penetrate skin result in a disease called cutaneous larva migrans. A. caninum may also cause a rare human infection known as eosinophilic enteritis.

Although skin penetration by "human" hookworm larvae is a classical textbook concept, infection is also caused by ingestion of eggs. Extrapolating from this, insufficient consideration has been given to what might happen when humans swallow "non-human" hookworm eggs, such as those of Ancylostoma caninum.

thanks for all.

Dear colleagues

One small note: if humans become infected after ingestion, as some pet animals do, the infective stage should be an L3, because eggs are morulated when shed in faeces and are not infective. These eggs will develop till they have an L1 inside, after some hours in the environment. Then L1 hatch and must go through two molts before reaching the L3 stage, the real infective stage.

These L3 can be easily ingested by children/adults eating raw vegetables in salads, or while doing geophagia, when playing on the ground without washing their hands or while doing gardening without gloves.

There are some eosinophilic enteritis reported in Australia since the 1990s, whose nematodes were collected and identified after colonoscopy, and after this report, parasitologists also began to consider both cutaneous and enteric syndromes caused by this agent in humans.

Best regards

Luís Carvalho

Parasitology and Parasitic Diseases

Faculty of Veterinary Medicine

Lisbon University

Portugal

At the time, enteric cases in Australia were related in theory to the cutaneous route of infection (although oral infection was not excluded). I believe that in the current state of knowledge, open-minded consideration should be given to the possibility of enteric Ancylostoma caninum cases being the result of infection via either of the two routes.

Dear Miles

I completely agree with your statement.

Thanks, Luis.

It is now becoming apparent that the animal-infecting parasite Ancylostoma ceylanicum is responsible for many more human intestinal hookworm cases than previously thought.

SEE: https://doi.org/10.1371/journal.pntd.0005734

Life Cycle:

Eggs are passed in feces. Larvae develop in soil to the infective L3 stage and then are either ingested by the host or they enter the host through cutaneous contact. The larvae migrate to the lungs, and then on to the intestinal tract of the host. In the small intestine, the larvae develop into adults. Eggs are then expelled with the feces and the cycle continues.

Alternatively, larvae may migrate in the host to subcutaneous fat, and in females, to the skeletal muscles and mammary glands. Once in these tissues, the larvae become inactive. When infected females begin to nurse offspring, the larvae are activated and passed to the young who become infected. This "trans-mammary route "of infection is of primary importance as younger animals are more susceptible to infection. Older animals often develop resistance to repeated exposures of the parasite. Thus, it is much more likely that young animals will be infected with the parasite than the older animals.

Finally, if a rodent ingests the L3 larvae, the larvae will migrate to the tissues and become dormant. If the rodent is eaten by a dog, the larvae will mature to adulthood in the small intestine.

The pre-patent period is two weeks.