Miles B Markus

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Questions related from Miles B Markus

What is the explanation for Plasmodium vivax malarial recurrence?

No, it is not merely hypnozoite activation or recrudescence as conventionally understood. This is a rhetorical question, because the answer is...

14 January 2019 2,527 15 View

Can primaquine fail to kill putative extra-hepatic dormant stages of Plasmodium vivax, resulting in malarial relapse?

Despite treatment with the anti-relapse drug primaquine, Plasmodium vivax malaria often recurs. One reason might be related to CYP 2D6 (Marcsisin SR, Reichard G, Pybus BS. 2016. Primaquine...

12 September 2016 5,395 12 View

Recurrent Plasmodium vivax malaria: How should genotypic homology in genetic epidemiological studies be interpreted?

This question is concerned only with recurrences that are neither reinfections nor recrudescences originating from persisting parasites in the bloodstream. Given these two exclusions, when a...

07 September 2016 2,106 2 View