Americans use intravenous brexanolon for postpartum depression, and there are some literature supporting its efficacy. Can we use it instead of ECT or ketamin to treat severe depression? Is there anyone who had experience using this steroid effectively for severe depression?
Brexanolone (SAGE-547 injection) in post-partum depression: a randomised controlled trial - PubMed (nih.gov)
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Brexanolone injection in post-partum depression: two ...
https://www.thelancet.com › lancet › article › fulltext
by S Meltzer-Brody · 2018 · Cited by 204 — We did two double-blind, randomised, placebo-controlled, phase 3 trials, at 30 clinical research centres and specialised psychiatric units in...
Brexanolone: A Novel Therapeutic in the Treatment of ...
https://ajp.psychiatryonline.org/doi/10.1176/appi.ajp-rj.2019.150201
Brexanolone is the first therapeutic option approved by the Food and Drug Administration specifically for the treatment of postpartum depression. Recent trials of brexanolone demonstrated its efficacy, with a limited side-effect profile and minimal drug-drug interactions.
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