I need to do Codon-optimized in the reverse translation part.
The idea is to measure the hydro- protein sizes in various solvents (eg. with high ionic strength, EtOH/Water, other organic/water solvents), then, due to the extremely low solubility of some...
28 January 2021 297 3 View
I'm going to perform RNA-sequencing of the zebrafish brain with three different treatments, which are naive fish, alcohol withdrawal fish injected with Saline, alcohol withdrawal fish injected...
08 December 2020 4,643 2 View
I downloaded the expression matrix data "GSE143416_Brain_data_TPM.txt.gz" of GSE143416 from Gene expression omnibus ( https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi). However, the first column of...
30 November 2020 1,304 3 View
First of all, I created a simple solid cubic structure with coarse mesh in ANSYS WB Modal modulus. With the boundary condition is set as 1 face fixed, the first 5 natural frequencies (fn) given by...
23 June 2020 9,836 13 View
I have a batch of molecular files(.xyz) now and want to optimize geometry of these molecules in batch. Is there some advice about how to process them in batch with Avogadro by using Python? Thank...
23 February 2020 632 4 View
As we know, due to the tendency to decrease the overall Gibbs free energy, grain boundaries in crystalline materials are subjected to thermal-induced migration, either through a diffusive flux of...
23 December 2019 3,272 2 View
Hi everyone, I'm currently working on bone-targeting polymeric nanoparticles for treatment of osteoporosis. Just wondering what kind of human osteoblast (or other bone cells) are best suitable for...
03 October 2019 9,077 2 View
I'm doing a meta-analysis in R with surgical patients. How do you do a meta-anlayis with longitudinal type studies?? We are looking at radiographic values preop, postop, and follow up (3...
26 July 2019 3,756 2 View
Dear Readers: May I ask a silly question regarding metric invariance. Some textbook authors claimed that when metric invariance holds, the comparison across groups of the unstandardized...
01 February 2019 1,671 1 View
I've read that you can only compare AMPA/NMDA ratio before and after drug treatment as the value itself doesn't mean anything. Is this true? Can you compare AMPA/NMDA ratio between mouse strains...
15 April 2018 3,543 1 View
I performed site directed mutagenesis, transformation, and then I sent out plasmids for Sanger sequencing and found out that there is extension of DNA just before the stop codon. I am not sure...
27 February 2021 547 3 View
I am interested in evaluating mesh optimization solvers that converge to high aspect ratio unstructured hexahedral grids. In other words, I am interested in a solver that optimizes warpage,...
26 February 2021 7,279 2 View
Hi, I am having trouble with a problem, in the field of Optimal Control and the generation of optimal time-series. Let's consider a system, whose dynamics are represented by dx/dt =...
24 February 2021 9,105 2 View
I constructed a synthetic DNA library (scFv, VH-VL orientation) with a 3' reporter and 8x histag. I cloned and expressed this gene following which I performed an ELISA. The ELISA results suggested...
19 February 2021 7,006 5 View
Hi RG community, Like the title shows ,i was wondering if choosing the GA for this kind of Optimizaiton is a good choice? For example we have a population of 100 (for 7-8 Optimization Variables),...
14 February 2021 1,160 7 View
Dear all, I am currently writing my master thesis where I am analysizing my data using path analysis and SEM in R (lavaan package). Now that I like to write up my results, I am struggling with...
04 February 2021 8,993 2 View
Do anyone have a full MATLAB code for structural topology optimization using Genetic Algorithm? Such as a cantilever beam? Could you provide some MATLAB code to me , a beginner for GA. Thank...
03 February 2021 3,789 5 View
Hi, everyone Could someone recommend papers about Particle swarm optimization (PSO technique), using MATLAB, please? Thanks in advance
03 February 2021 3,811 6 View
Dear researchers, I am coupling Design Optimization with ANSYS Fluent in Workbench 2020 R2. I can do the analysis. I am patching the initial Temperature values of the zones. However, the patch...
28 January 2021 4,265 2 View
I am working on solving an optimization problem with two objectives by using neuroevolution. I use NEAT to evolve solutions which need to satisfy objective A and objective B. I tried different...
27 January 2021 4,875 3 View
