I have got Sigma aldrich's sodium hypochlorite solution (Pdt. Code: 239305) with available chlorine percentage of 4-5% and density of 1.097 g/mL.Can anyone suggest me how to calculate the concentration of it??
Aldosterone is a key player in this control network, although traditionally it was considered simply an endocrine mediator for enhancing sodium reabsorption across certain epithelia. Now it is known that this hormone can influence nonepithelial tissues, including the brain, where it may promote short-term physiological and behavioral adaptations in response to low-sodium conditions as well as chronic, maladaptive responses in pathophysiological states. ( PMID: 16002531 )
Elise P. Gomez-Sanchez at the UMMC who I personally met her showed that;
A small proportion of brain mineralocorticoid receptors (MR) mediate control of blood pressure, water and electrolyte balance, sodium appetite, and sympathetic drive to the periphery. Circulating inflammatory cytokines modulate MR-mediated changes in sympathoexcitation. Aldosterone binding to MR in the brain occurs, despite concentrations that are 2–3 orders of magnitude less than those of cortisol and corticosterone, which have similar affinity for the MR. The possible mechanisms for selective MR activation by aldosterone, the cellular mechanisms of MR action and the effects of brain MR on hemodynamic homeostasis are considered in this review. MR antagonists are valuable adjuncts to the treatment of chronic cardiovascular and renal disease; the crucial need to discover targets for development of selective therapy for specific MR functions is also discussed.
(PMID: 21429762)
And it worth to read the following recently published paper about Article Aldosterone and Mineralocorticoid Receptor System in Cardiov...
The percentage "available chlorine" is 4-5% Cl2. Therefore say 4.5% (mean of the provided range).
4.5% solution is 4.5 grams Cl2 in 100 ml soln
Let's say the concentration of sodium hypochlorite solution (aka bleach soln) is "X%" (i.e. Xg of NaOCl in 100ml soln).
The calculation corresponding to converting the available chlorine percent (i.e. 4.5%) to the concentration of sodium hypochlorite solution (i.e. X%) is attached as an image
The concentration of sodium hypochlorite solution (i.e. X%) = 4.7246%
You can also refer to Bleach Analysis by University of Idaho (https://www.webpages.uidaho.edu/chemlabservices/Chem%20112%20Lab/labs/Bleach.pdf)