Immobilization of gold nanoparticles to functionalized substrates. Refer some references to understand the mechanism of growth of gold nanoparticles and chemistry for affinity and binding to funcitonalized substrates.
It depends on how the substrate is functionalized, and what is coating the gold particles. They can bind covalently through thiols or the use of chemical crosslinking, or electrostatically if the surface is rich in amines, or hydrophobically, or through protein-protein interactions or protein-rna interactions etc.. it's really kind of limitless depending on the coatings and solution environment. This is in part why there's so many different protocols for gold nanoparticle self-assembly on surfaces.
This a publication about the effect of organic layers (Amine Vs thiol functions ) on grafting GNPs on surfaces
Article Optimizing the immobilization of gold nanoparticles on funct...
Dear Adam Hughes, I totally agree with you. Could you refer some references to understand the same and effect of different reductants on gold nanoparticles and their affinity to functionalized substrates.
So, is the affinity of gold nanoparticle to Thiol (-SH) higher than the affinity to amino (-NH)? what is the strength of Au-S and Au-N bonds?
Thanks in advance!
Hi All,
Please can anyone suggest how I can recover gold nanoparticles immobilized on bare Si wafer.
I have tried dipping the substrate in water followed by sonication.
Thanks!
Thanks Justas for your suggestion. I did think of that but since I am more interested in collecting the particles (probably via centrifugation) I am thinking of a suitable etchant that I can drop on my wafer and subsequently withdraw the solution with the Au NPs dispersed in it. Centrifuging such small amount of etchant could make it easier to retrieve the NPs.
- Badges
- Science topic
- Similar topics
- Psychology
- Mental Processes
- Learning