One piece of equipment used in clinical laboratories, specifically in the field of medical laboratory science, is the Sysmex DI-60 Morpohology Analyzer. It was created and is still being researched by scientists and researchers to meet the need of expediting the acquisition of test results for procedures like WBC differentials, Complete Blood Counts (CBCs), cell image analysis of RBCs and WBCs, slide preparation, and others. The invention of the Sysmex DI-60 is a significant discovery that aims to reduce the workloads of medical laboratory scientists by allowing laboratory personnel to concentrate on other duties, such as confirming results or carrying out further tests while the instrument is operating.

According to the aforementioned remark, the Sysmex DI-60 is still undergoing improvement because it still has certain drawbacks. As to Oh Joo Kweon et al.'s study article "Red and white blood cell morphology characterization and hands-on time analysis by the digital cell imaging analyzer DI-60," the device yields consistent outcomes that are less susceptible to variations in operator proficiency. Discrepancies in the results exist in the WBC differential counts obtained in Sysmex DI-60, particularly with regard to basophils. The sensitivity of DI-60 in detecting atypical lymphocytes and normoblasts was not up to par. The RBC characteristics of cells displaying hypochromia, anisocytosis, microcytosis, and macrocytosis were similarly found to have poor sensitivity and specificity. These are only a few of the documented drawbacks that were noted throughout the machine's investigation.

The Sysmex DI-60 digital morphology analyzer has several downsides, but it also provides numerous benefits to medical laboratories, such as automation, standardization, efficiency, and increased accuracy in blood cell morphology analysis.

Benefits:

Disadvantages:

References:

Nam, M., Yoon, S., Hur, M., Lee, G. H., Kim, H., Park, M., & Kim, H. N. (2022). Digital Morphology Analyzer Sysmex DI-60 vs. Manual Counting for White Blood Cell Differentials in Leukopenic Samples: A Comparative Assessment of Risk and Turnaround Time. Annals of Laboratory Medicine, 42(4), 398–405. https://doi.org/10.3343/alm.2022.42.4.398

‌Yoon, S., & Hye Ryoun Kim. (2023). Analytical performance of the digital morphology analyzer Sysmex DI-60 for body fluid cell differential counts. PloS One, 18(7), e0288551–e0288551. https://doi.org/10.1371/journal.pone.0288551

Sysmex DI-60 has contributed in the medical field for some time. Since its invention in 2013, the Sysmex DI-60 done its part in performing blood counts, reticulocyte counts and even scanning and taking photograph of the entire PBS. One of its advantages is its quick turnaround of results which leads into increased efficiency in work. However, its disadvantages is it provides a acceptable result and it lacks in other RBC parameters which can affect the result.

References:

Kweon, O. J., Lim, Y. K., Lee, M. K., & Kim, H. R. (2022). Red and white blood cell morphology characterization and hands-on time analysis by the digital cell imaging analyzer DI-60. PloS one, 17(4), e0267638. https://doi.org/10.1371/journal.pone.0267638