How can we prevent a fracture of an atrophic mandible in an elderly patient who has progressive osteomyelitis?

Tooth extraction and subsequent dental implant placement in Sprague-Dawley rats induce differential changes in anterior digastric myofibre size and ?

01 March 2021 7,254 3 View

What is the exact mechanism of the antimicrobial effect of local anesthetics?

The antimicrobial effect of local anesthetics has been known for more than 50 years, but it still seems to have an unclear mechanism of action. which bacteria? which concentration? etc etc. ....

27 February 2021 4,450 2 View

I have a problem with kanamycin - why the kanamycin doesn't affect?

Hi everyone, I need to expression of GFP with pET28 plasmid in E. coli BL21(DE3) plysE. Transformed cells have kanamycin and chloramphenicol resistance. Normally, only transformed cells should...

22 February 2021 4,032 4 View

Can 5-FOA Diffuse Through Agar?

I am preparing to do a gene knockout in the filamentous fungi Coccidioides posadasii targeting pyrG/URA3 so that 5-FOA can be used for selection pressure instead of traditional antibiotic...

16 February 2021 169 4 View

Which Journals would you advise to submit a Letter which briefly talks about neurosurgical treatment of neuro-oncological patient during Sars-COV-2?

Possibily not an open access journal which does not add any publishing costs once being accepted. Thank you in advance

09 February 2021 717 6 View

Separated objects vs Non-Manifold Assembly?

I'm trying to do a simulation between the Maxilla and the Mandible I converted the Dicom file from the CT scan to a CAD module and module the articular discs via 3d software. I have two options...

08 February 2021 8,731 2 View

What are the naitve functions of bacterial NRP?

The bacterial NRPs (nonribosomal polypeptides) are famous as clinical drugs such as antibiotics, but is there other native function of these NRPs of bacteria except antimicrobial, because their...

01 February 2021 4,280 1 View

The First Survey Addressing Patients with BMIs over 50?

Dear Bariatric Surgeons, The importance of obesity management in patients with BMIs over 50 has not been completely addressed and it should be considered separately from patients with morbid...

20 January 2021 2,748 1 View

Does anyone know of a protocol where Sunitinib is directly injected into a tumor in xenograft models?

I'm fairly new to cancer research and there's a host of articles on Sunitinib being administered via oral gavage in mice models but I'm unable to find any information on studies that have explored...

10 January 2021 8,437 3 View

Why I am not getting cultures of DH5 alpha and BL21 cells after transformation?

Even if I get them cultured colonies are very less and almost not transferable and grows very slowly in the media. I checked cells by transforming with control vector. I changed antibiotic also...

06 January 2021 1,013 3 View

Fabien Bornert

I think we can't avoid this kind of complication. Antibiotics and HOT seem to be the best way with regular follow up. It is a palliative therapy. We have a similar problems with patients affected by ONJ in association with bisphosphonates drug.

Richard J P R van Merkesteyn

treat the osteomyelitis according to the existing protocols. Sequestrectomy and IV-antibiotics will give good results. in suppurative osteomyelitits no benefits are to be expected from HBO. stabilize a possible pathologic fracture with non-invasive means whenever possible.

Mouetaz Kheirallah

It is thought that osteomyelitis is decreasing in prevalence due to broad-spectrum antibiotic treatment; however, it still remains a challenging clinical entity in developing countries. I think stabilization with non-invasive means is a good way.