Are any database collected cell penetrating anticancer peptides ?

Dear researchers, Anticancer peptides(ACPs) with cell-penetrating properties can enter to cytoplasmic space of cancer cells and induce cell death. but, I could not find the database that...

29 January 2021 707 3 View

How to calculate DNA concentration of a sample with high concentration buffer?

I want to calculate the concentration of DNA in an unknown sample. But it's buffer has a high concentration and our nanodrop don't accept that as a blank of dsDNA. Thus I dilute the buffer with...

23 January 2021 9,440 2 View

I am planning to start a prevalence study on CSOM in gilgit baltistan region . how shoud i calcuate the sample size ??

i need to find out the sample size as no research has been done on this topic so no stats are available and how can i tailor the research for use in hospital setting ???

19 January 2021 5,572 5 View

Can DNase1 degrade the plasmid (circular) DNA?

I had a sample of plasmid extracted from e.coli and wanted to check the amount of Host cell RNA impurity with a fluorescent dye. to do this, first of all, I treated the sample with DNase I. (NEB...

11 January 2021 2,608 3 View

What is the outcome of research for researchers?

For the past few years I have been in doubt and a question about the nature of research always occupies a part of my mind. As researchers, we have been asking and researching for years. We may...

17 November 2020 4,505 11 View

How can I do y-scrambling( y-randomization) to test the developed machine learning-based model ?

Dear researchers : y-randomization is one of the special tests of machine learning approaches. I want to evaluate my developed machine learning-based models, to predict active peptides, by...

26 October 2020 1,196 2 View

How i can get rid of phenolic contamination (low 260/230 ratio) in RNA extraction from blood by using Gene All TRIZOL (Ribo LS)??

in this work i use the standard protocol in extraction& good sampling and use chloroform and twice wash with ethanol 75% but i have phenol contamination (low 260/230 ratio) for example: OD:...

21 September 2020 8,408 3 View

How can I find some material (books, articles and etc.) to do and write a systematic literature review(SLR)?

I need to review theories of moral decision making in a systematic method to find different definitions and models of that. I have read some guidelines about the systematic review and...

30 June 2020 3,087 13 View

How to calculate erosion in LS-DYNA?

I am modelling an impact on a Ti64 block. The impacting particles are rigid and the Johnson-Cook material has been used for the block. I am wondering how to calculate erosion; I want to analyze...

13 April 2020 4,509 2 View

Is there any labeled public dataset for COVID-19 ?

Hi, do you know any resource for accessing data-sets about the symptoms and conditions of people who tested positive or negative for the Corona virus ?

03 March 2020 508 6 View

How to calculate the annealing temperature of a primer pair?

I have to amplify a gene and my primers just reached. The Tm for Forward primer is 64.2, and that of reverse primer is 65.5. Can some one suggest how to get the best annealing temperature? Thanks...

01 March 2021 360 7 View

How can i resolve the "final solutuin is not converged" error in Comsol for my heat transfer simulation??

I have been trying to simulate heat transfer problem in Comsol 5.5 for long time but it always throw an error stating: "Failed to find a solution. Maximum number of Newton iterations...

28 February 2021 8,626 3 View

High aspect ratio hexahedral mesh optimization solver?

I am interested in evaluating mesh optimization solvers that converge to high aspect ratio unstructured hexahedral grids. In other words, I am interested in a solver that optimizes warpage,...

26 February 2021 7,279 2 View

Error in comsol?

Dear respected researchers, while performing CFD analysis in Comsol it's showing like this Error: Nonlinear solver did not converge. The maximum number of Newton iterations reached can...

24 February 2021 249 3 View

Implementation of chance-constrained optimization problem via scenario approach?

23 February 2021 7,826 2 View

Should I use Pressure Based Solver or a Density-Based Solver?

Dear researchers, I want to simulate a flow (air) in a wind tunnel, and I want to integrate a fluidic actuator inside it in order to control the separation of the boundary layer. At the blower...

22 February 2021 4,882 3 View

Is it okay to mention you distributed your qualitrics study link through social media sites?

Just want to be clear and know it is okay to say I have distributed the qualitrics link through social media such as Facebook, Instagram and Twitter to ensure my target audience is reached in my...

21 February 2021 5,143 2 View

Could the "incoming radiation (net radiation)" values be negative?

Could the "incoming solar radiation" values be negative? What is the difference between "global solar radiation" and "incoming solar radiation"? Which one might be measured negative values?

21 February 2021 7,726 9 View

Who are the possible experts I can reach out to regarding the reseach topic: Activated Carbon as Water Filter?

Hi! Me and my team mates are currently new in doing a research study. We do not have any previous experiences in research. And we just wanted to know what type of experts (the field they in) can...

19 February 2021 9,596 4 View

Comsol Maximum number of Newton iterations reached?

Comsol is investigating deformation due to gravity. Gravity is applied to the nanosheets to check for displacement and stress. If I input the Young's modulus of the channel to about 1 [GPa], the...

15 February 2021 6,027 3 View