How can I measure the amount of drug degradation after release of nanoparticles?

More Marjan Motiei's questions See All

Can anyone share UMATHT subroutine?

I want to see the format of formulation in your code, so i can write for my own problem. U, DUDT, DUDG(NTGRD), FLUX(NTGRD), DFDT(NTGRD), DFDG(NTGRD,NTGRD)

04 August 2020 5,268 4 View

Can there be a positive correlation In the following situation?

The results showed low expression of A and overexpression of B in Tumor tissues. We expect them to show a negative correlation, but they show a significant positive correlation. Can you explain...

06 March 2020 3,149 11 View

Do you prefer a really complicated manuscript with too many jargon in it or a really well-written concise one?

It takes 1 min to translate everything but it takes 25 years to know if it has translated correctly. I had a client, a pharmacy graduate, called Dr. Grand (for ethic's sake, I'm gonna call her...

29 November 2019 3,603 8 View

Why we have not Repeatability in HPLC results?

I'm studying hormonal adulterant in the dietary supplement. At the beginning of validation, I inject the concentration series of hormone standards. But I had not repeatable result in an injection...

05 October 2019 8,695 2 View

Carboxylic acid react with amine? Condition??

hi i'm going to do a reaction between Carboxylic acids and amine. is there any body who can introduce some papers or something to find out that we need how much of each component ?? and what is...

16 September 2019 8,176 8 View

The best model for Thermal Conductivity prediction of aligned BN aerogels?

I'm looking for a prediction model which considers the effect of shape of fillers, their orientation, interfacial thermal resistance and interaction between the fillers. Most of models are for...

26 June 2018 1,364 2 View

How does the solubility of carboxylic type of surfactants in water change with chain length? What is the pH effect ?

I want to know if surfactants with higher chain length get dissolved in water at high pH. Can you please suggest references?

30 November 2014 9,462 3 View

How can I extract the object from the background in a fast way?

I need a fast approach for object localization in kind of images used in the industry, which are related to different parts of car and the goal is to categorize them in different classes. At the...

11 October 2014 9,838 18 View

What is the sampling method for my quantitative survey?

I listed events from which samples of a study were taken. I do not know the whole population. I participated in all of them during 6 months and I gave the questionnaire to all of the people who...

14 May 2014 1,590 12 View

The primers with high TM temprature

I designed a primer with high Tm temperature (74, 70) [I could not find a better primer. In addition, before PCR, I have to do RT-PCR to convert RNA to c DNA] 1. What kind of PCR do you suggest...

18 October 2011 3,888 1 View

I need to image mesoporous silica nanoparticles that are in ~100 nm size and do high resolution TEM to look at mesopores. what grids should I use?

Need to image mesoporous silica nanoparticles using the TEM. Also, need high resolution TEM images to see the mesoporous structure. Kindly suggest what kind of grids to use. Thanks, Shatadru

02 March 2021 1,787 2 View

Can chitosan alone can act as a reducing agent for Cu(0) nanoparticle sythesis?

[Synthesizing Cu nanoparticles without using chemical reductants]

01 March 2021 8,359 1 View

What are the new 2D nanomaterials were used for Silver nanoparticles stabilization?

In the stabilization of AgNPs are vital in current research interest. However, some of the 2D nano-materials like graphene oxide, MoS2, etc... previously used to stabilize it. But still they shown...

01 March 2021 2,207 3 View

What is the state of the drug inside solid lipid nanoparticles (SLNs)?

I am a little confuse with the mechanism of solid lipid nanoparticles (SLNs). The main point of encapsulating drugs into SLNs is because some drugs have low solubility in water. Therefore, SLNs...

01 March 2021 3,703 3 View

How to check the uv-vis absorption of nanoparticle by surface plasmon resonance?

I try to check the uv-vis absorption of Indium nanoparticle. Now I am measuring in solution, can I measure it in the form of a film?

01 March 2021 930 3 View

How does an antibody have full intact antibody + half antibody?

Hello, I was just wondering how does a antibody have full intact antibody + half antibody? Is it because of the drug conjugation?

28 February 2021 1,577 1 View

Distribution of particles in metal matrix?

How would define the "good" and "poor" distribution of particles within the matrix. Is there a quantitative solution to assess the distribution of the particles, which then having denotation of...

28 February 2021 7,397 8 View

How can I calculate the rdf of water molecules around 'Na' ions that are closest(adsorbed) to the nanoparticle(solute)?

Hi, I want to calculate the radial distribution function for water molecules around the Na+ ions adsorbed on the surface of a spherical nanoparticle using the gromacs trajectory dynamically? For...

28 February 2021 5,650 1 View

LEDs on Vis Light photo degradation of MB water sol via N doped TiO2 in a mini flume?

Good day to all, I have no experience with light emitting diodes. I am building a glass mini flume to demonstrate the photo degradation of Methylene Blue in water running over self cleaning...

26 February 2021 4,026 5 View

Can anyone share his experience regards Smoothing in origin?

I am working on TiO2 composite material and the results of XRD have a lot of small/junk peaks and while I apply a smooth filter in Origin then the other characteristics peaks disappear so anyone...

26 February 2021 8,183 3 View

Marjan Motiei

Dear Curtis Guild

, you mean I should prepare release medium containing drug and drug loaded nanoparticles, which the amount of free drug and encapsulated drug are in equilibrium? I think it will show the same problem, because there will be degradation in both free drug and released drug...

Maria Ashraf

you can first take UV-Visible spectra of the drug by placing it photocatalytic reactor and then add NPs in this solution and take UV-Visible spectra Again and again and then you can easily get the graph of degradation of the drug in the origin. best of luck