I can't prepare the hydrogel using low MW CS of (pH, gelation point etc.) with the same protocol as I was getting with Medium MW CS. Should i reduce the concentration of CS and reduce the conc. of acid solution for dissolving CS and also suggest how cross linker concentration will vary in case of low MW CS? Thanks!
Martin Beaulieu
When I have done a chitosan with a low MW, I've maintained the same concentration of acid and chitosan but I have increase the time of hydrolysis at 80°C.
When you produce a chitosan with low MW, you increase the probability to cut a cross linker, so I think that the cross linker will be lower.
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