How can I insert a protein structure model within the Lipid bilayer structure model? Kindly help.
Hi, Sunidhi Bhatt
You can use molecular dynamics simulations
Article The lipid bilayer membrane and its protein constituents
https://www.sciencedirect.com/science/article/abs/pii/S0959440X08000304
I believe you can use the membrane builder tool at CHARMM-GUI.
Check out these Youtube videos:
CHARMM GUI tutorial - https://www.youtube.com/watch?v=0S2at9O4ieY
Gromacs tutorial - https://www.youtube.com/watch?v=v7GRmRheuto
I have prepared an excel sheet to calculate yield moment and curvature for a hollow circular section. In which Depth of Neutral Axis is fixed using "GOAK SEEK" function. Axial Force is input of...
22 November 2020 4,632 3 View
I have perform some protein-protein docking studies. I used Hdock, Prizm. But I am unable to find a proper method to verify my docked structure. I also docked my structure in Hex program to get...
19 October 2020 4,083 7 View
I am learning markov state model in jupyter notebook. When I am fetching data with mdshare.fetch() command from tutorial its okay. But how I will fetch XTC and PDB File from my local source. Which...
10 August 2020 5,379 3 View
I am doing MD simulations for protein. When i am running the commands the following error is occurred Command which i have used with ubuntu gmx genion -s ions.tpr -o solv_ions.gro -p topol.top...
27 July 2020 3,199 15 View
Hi, I am looking mouse ELISA kit for the evaluation of creatinine level in serum and urine. Could you please suggest me which kit is most reliable for this assay? Regards, Nirmal
03 December 2019 824 4 View
Zirconia or Zirconium NaNo Powder Production
26 November 2019 2,247 3 View
I am not able to hook up my table of ISOBARIC (225 Bar) PROPERTIES OF SUPERCRITICAL WATER (varying wrt Temp) obtained from NIST into ANSYS FLUENT which only accepts a C Code, Piecewise Linear and...
27 October 2019 4,424 5 View
Hi I am following a paper "Development of CHARMM-Compatible Force-Field Parameters for Cobalamin and Related Cofactors from Quantum Mechanical Calculations". In this paper they used charmm force...
25 September 2019 8,059 7 View
As in case of capacitance calculation for super-capacitor the CV charge discharge method is popularly used. Can the similar method be implement to calculate the capacitance for graphene based...
27 August 2019 2,843 5 View
I have prepared a thin PLCL film by solvent casting technique. The solvent I used is acetone. I am getting a sticky film even after heating the film at 90DegC for 3-6hrs. Please suggest any...
08 August 2019 6,017 1 View
The term miscibility refers to the single-phase state in thermodynamics. I do not mean the compatibility of different components. To determine the miscibility I know several techniques such as...
03 March 2021 4,107 4 View
Hi, I am trying to construct a multi-layer fibril structure from a single layer in PyMol by translating the layer along the fibril axis. For now, I am able to use the Translate command in PyMol...
02 March 2021 4,569 4 View
Hello! I have a dataset of n=3000 nested within 8 countries with approximately 200 or 400 responses in each country. I originally planned to perform multilevel modelling with 4 dependent variables...
02 March 2021 6,865 1 View
It is oftentimes said to be a distinctive metallographic trait that differentiates a fully austenitic and a fully felly ferritic steel without etching that might distinguish between two. Why...
02 March 2021 728 2 View
Hello everyone, I had run a mediation model in SmartPLS using questionnaires that were already validated among my statistical population. A professor who edited my paper -though she is not...
01 March 2021 3,052 3 View
In the sem analysis of CaCO3 nanaoparticles, the morphology images showed spherical shaped particles but the proposed morphology for these type of nanoparticles is trigonal. I prepared the...
01 March 2021 1,960 4 View
I have designed reflectarray element to generate OAM beams at 5.8GHz and feeding it though Horn Antenna on HFSS. After full wave simulation, i am not getting desired results i.e Radiation pattern...
01 March 2021 9,701 5 View
I have a set of stably transfected cell lines all transfected with plasmids containing GFP tags on the C terminus. During a western blot using anti-GFP antibody, one of my plasmids has dissociated...
01 March 2021 9,310 4 View
I am a little confuse with the mechanism of solid lipid nanoparticles (SLNs). The main point of encapsulating drugs into SLNs is because some drugs have low solubility in water. Therefore, SLNs...
01 March 2021 3,703 3 View
Hi, I am running a size exclusion chromatography experiment with a buffer containing Potassium Acetate as a salt. I analyse these fractions through SDS-PAGE. After boiling my SEC fractions in...
01 March 2021 2,622 3 View