Does anyone have any idea if estrogen (hormone) is fed to cell for certain amount of weeks and will it increase the expression of estrogen receptors (ER)? And can anyone send me paper for similar work being done?
Dear Bazai, you want increase Estrogen receptor in Cell culture or animal?
Anyway inducing of Esterogen receptor can be perform in some ways:
1) Estrogen induces its receptor, so you can treat the cell by E2
http://www.ncbi.nlm.nih.gov/pubmed/18174157 (free full paper)
http://onlinelibrary.wiley.com/doi/10.1111/gtc.12214/abstract
http://www.jbc.org/content/283/11/6752.full.pdf
2) Estrogen receptor (ER) inducing by siRNA:
http://www.ncbi.nlm.nih.gov/pubmed/19082494
3) ER inducing by genistein:
http://www.ncbi.nlm.nih.gov/pubmed/12297547 (Free full text)
4) Arsenic can induces ER:
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0035957
5) Dioxin can induce ER:
http://molpharm.aspetjournals.org/content/69/5/1599.full (free full text)
and some other methodsssss
best
mehdi
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