R M Bazai

12 Questions 3 Answers 0 Followers

Questions related from R M Bazai

Paracetamol impurities method?

Hi can anyone suggest me robust isocratic or gradient robust method for paracetamol impurities, I modified the BP method but 4aminophenol and paracetamol giving me peak tailing. Mobile phase A...

15 November 2018 9,219 0 View

Does anyone help in paracetamol impurities method?

I am trying to develop method for paracetamol impurities in oral suspension,at the moment I am using 20mM phosphate buffer but everytime the same mobile phase and same solution give me different...

12 November 2018 482 0 View

How to detect Potassium nitrate on TLC?

Dear Researchers I have been trying to detect the potassium nitrate on TLC but could not detect it at all, could anyone give me an idea of any staining method specificity for detection of...

05 December 2016 7,117 7 View

Does anyone know the curretn Aromatase inhibitor in clinical trial?

HI Does any one know the current drug candidates for aromatase, 17beta-HSD3 and 5alpha-reductase in clinical trial.

10 May 2016 4,021 1 View

Can any one share their knowledge, why the peripheral zone of prostate cancer ?

Why the peripheral zone of the prostate gland is said to more affected by prostate cancer than the other zones such as central and transitional zones.

03 April 2016 3,309 6 View

How do you find out the enzyme turnover number in cell based assays?

Does anyone can please explain how to find out the enzyme turnover no in cell based assays.

29 April 2015 6,953 1 View

Why is 17B HSD-3 called type 3, I do not understand the 3 and likewise other isozyme type 1 and type 2?

Hi Can any one explain why the 17B HSD3 is called type 3?

01 April 2015 8,597 1 View

How can I increase the expression of desired receptors?

Does anyone have any idea if estrogen (hormone) is fed to cell for certain amount of weeks and will it increase the expression of estrogen receptors (ER)? And can anyone send me paper for similar...

06 March 2015 9,996 2 View

What is the relation between breastfeeding and reduced risk of breast cancer?

Can any one explain what is the exact link between the breastfeeding and reduce risk of breast cancer. Some researchers are of the view that breastfeeding delays the menstruation cycle which could...

16 February 2015 3,702 14 View

Why is the R enantiomers of Aminoglutethimide a potent AR inhibitor?

Why is R enantiomers of Aminoglutethimide a more potent AR inhibitor than S enantiomers

05 December 2014 944 3 View

Can somebody please explain to me how steroidal Aromatase Inhibitors (formestane) and Non steriodal (Letrozole) binds to Haem of the enzyme?

15 November 2014 2,236 1 View

Which kind of ion pair agent for determination of paracetamol impurities would be the best option in mobile phase?

Hi dear I am working with development of paracetamol related substances by HPLC. The impurities include 4 Aminophenol, 4 Nitrophenol and 4 chloroacetinilide. since i have tried 0.05M of...

01 January 1970 2,576 3 View